Oscar winner will act opposite her daughter Mia Threapleton in the first episode of season 3 of female-led anthology series I Am.
The Channel 4 series has previously starred in and in I Am Victoria, while Samantha Morton was nominated for a Bafta for .
I Am Ruth sees the take the lead in the series’ first feature-length episode, with filming set to begin at the end of April.
Mia, 21, is Kate’s eldest daughter, who she shares with first husband, film director Jim Threapleton.
The couple was married between 1998 and 2001.
She is also mum to son Joe, 18, with second husband, Bond director , and eight-year-old son Bear with current husband Edward Abel Smith.
Although her most high-profile role to date, Mia already has acting credits to her name, including TV series Dangerous Liaisons and independent film Shadows, in which she played the main part.
She has also acted opposite her mother previously, making an appearance in the minor role of Helene in 2014 film A Little Chaos, which also starred the late Alan Rickman and .
Kate previously revealed that Mia had started acting .
Speaking to Lorraine Kelly last April, she explained: ‘What’s great for her is she has a different surname so she slipped under the radar and the people who cast her didn’t know she was my daughter and that was important for her self-esteem, of course.’
I Am is created, written and directed by Bafta-winner Dominic Savage, also known for drama The Escape, with the stories for each film developed alongside its leading actors and including semi-improvised dialogue.
Kate described herself as ‘excited an honoured’ to be taking part in a British TV project.
‘I have always admired Dominic’s work and, in particular, his commitment to telling real stories,’ she said. ‘British television is at an all-time high, and I feel excited and honoured to be part of this community, especially right now.’
reports that I Am Ruth will depict tension between a mother and daughter, who is obsessed with online influencers.
Other cast members are yet to be announced, along with details of the other two films in the trilogy.
Creator Dominic commented: ‘It is a complete honour for me to be working and collaborating with Kate Winslet on this first film of the new series of I Am for Channel 4.
‘Kate is such a legend, such an incredible and sublime acting talent, and I can’t wait to start shooting this unique and important story that we have created together.’
Caroline Hollick, Channel 4’s head of drama said the collaboration between Kate, Mia and Dominic had ‘produced a compelling, heart- rending and ultimately very relatable character for our times in Ruth’.
Other actresses who have appeared in the anthology series so far include stars Gemma Chan and Letitia Wright, and Oscar-winner Lesley Manville.
I Am Ruth’s broadcast date is yet to be announced.